Q: Whats the best measure of titrating Atropine drip in Organophosphate poisoning?

Answer: Control of hypersecretions served as the best monitoring parameter for titration of the drip rate. Organophosphate (OP) toxicity itself is a clinical diagnosis. There is no clinical lab value which can be followed except for above clinical objective finding. Following mnemonic can be used to remember the muscarinic effects of organophosphates.

SLUDGE: salivation, lacrimation, urination, diarrhea, GI upset, emesis

DUMBELS: diaphoresis and diarrhea; urination; miosis; bradycardia, bronchospasm, bronchorrhea; emesis; excess lacrimation; and salivation.