Preparation of NOREPINEPHRINE

NOREPINEPHRINE (LEVOPHED) drip should be prepared in dextrose containing solution (D-5). NOREPINEPHRINE (LEVOPHED) is less stable in normal saline and loose its potency from oxidation over hours. Dextrose containg solution is preferred as the dextrose protects against oxidation of the norepinephrine and keep it active and stable.